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Suzhou Nanomicro Technology Co., Ltd.

Suzhou Nanomicro Technology Co., Ltd.
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Silica Gel for Chromatography UniSil 1.7-100

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  • Product Description
Product Attributes

Model No.UniSil 1.7-100

Pore Size100 Å

Supply Ability & Additional Informations


Payment TypeL/C,T/T


UniSil® is a series of monodisperse spherical porous silica gels used for chromatography, produced by Suzhou Nanomicrotech Co. Ltd. from its unique patented technology that is developed in-house. UniSil® series of products meets the requirements of high performance liquid chromatography (HPLC) analysis in the laboratory and preparative separations in industry scale. The monodisperse spherical porous silica gel has distinct advantages, such as highly uniform particle size, perfect sphericity, outstanding mechanical strength, easy column packing, high column efficiency, good resolution, and low back pressure, UniSil® has already been widely used in analysis and Separation Of Organic Compounds, natural products, and large biomolecules. Nanomicrotech is proud to be the leader of monodisperse chromatography silica gel with capability to produce in commercial scale.

Silica Gel for Chromatography

Figure 1. SEM micrographs of UniSil® monodisperse chromatography silica gel

Features and Benefits of UniSil®



High uniformity of particle size and perfect spherical shape

Easy column packing, low back pressure, high efficiency and resolution

Optimal pore structure

High loading capacity and high selectivity

Unique surface bonding technology

Good acid and alkaline resistance, broad application pH range

High mechanical strength

Robust column packing and repacking, long lifetime

Large scale production

Consistent product quality, short delivery circle

High uniformity of particle size and perfect spherical shape

UniSil® silica gel media are made to in precise particle sizes with exceedingly high uniformity and perfect spherical shape (Figures 2 and 3). When compared to other commercial chromatography silica gels ( with broader particle size distribution), UniSil® has great advantages of easy column packing, low back pressure, high column efficiency, good resolution, stable column bed and reduced frit plugging.

Chromatography UniSil

Figure 2. Comparison of UniSil® and well-known international brand chromatography silica gel

Silica Gel UniSil

Figure 3. Particle size distribution of UniSil® and well-known international brand chromatography silica gel

Chromatography separation and purification

Figure 4. Flow characteristics in Chromatography Media of different particle size distributions

Optimal pore structure

The pore structure of silica gel has a great influence on its mechanical strength, separation ability, and loading capacity. Nanomicrotech not only controls precisely the particle size and size distribution of the silica gel, but also optimizes pore structure forming, desired surface area and pore volume. As the result, UniSil® silica gel has high loading capacity, strong mechanical strength, and superior separation capability.

Unique surface bonding technology

The selectivity and lifetime of a silica gel are often determined by the bonding phase on its surface and end-capping. In addition to the world leading technology of making silica gel, Nanomicrotech has developed unique techniques of surface bonding and end-capping, which enable UniSil® to be used with a broad pH range of application, good separation selectivity, and peak symmetry. To meet customer needs, Nanomicrotech also provides a variety of polar and non-polar bonded phase silica gel(C18,C8,C4,Phenyl,NH2,CN,Diol).

Figure 5 showed the separation of various chemical substances by UniSil® 5-120 C18 reverse phase silica gel media, including pyridine (alkaline compound). The high column efficiency and sharp and symmetric peaks indicated the minimal residual silanol groups on the surface (due to good end-capping).

Monodisperse microspheres

Figure 5. Chromatographic separation of various compounds by UniSil® 5-120 C18

Exceptional chemical stability and resistance against acid and base

Nanomicrotech`s unique bonding and end-capping techniques gave UniSil® exceptional resistance to acidic and alkaline environment. Figure 6 showed a comparison of UniSil® 10-100 C8 with a leading commercial brand, in terms of column efficiency (after alternating elution of columns with acidic and alkaline solutions). The results indicated that the column packed with UniSil® maintains the column efficiency much better than the other with commercial silica gels, suggesting a stronger resistance against acid and base.

HPLC analysis

Figure 6. Comparison of column efficiency, between UniSil® 10-100 C8(green)and leading commercial brand(red), after treatment with acid and base

Large scale production capability and lot-to-lot consistency

State-of-the-art manufacturing facility at Nanomicrotech allows a large scale production of UniSil® to meet the demands of industrial separation. Good quality control system also assures the high quality and good lot-to-lot consistency (as shown in Figure 7).

HPLC packing materials

Figure 7. Lot-to-lot consistency of UniSil® silica gel


Nanomicrotech has an in-house application development group with vast experiences. This group provides customers with a lot of technical services, from process development to technical transfer for production (industrial scale). UniSil® silica gel media have been successfully applied to the isolation and purification, including plant extracts(huperzine A, ginkgolide, panax notoginseng saponins), antibiotics(vancomycin, daptomycin, caspofungin, tiacumicin, Pneumocandin B0, cyclosprin, erythromycin), polypeptides (tacrolimus, thymalfasin, bivalirudin)and others(cod liver oil, bortezomib, flurbiprofen axetil), etc.

List of Products

Nanomicrotech supplies spherical silica gel media in the size range of 1.7 to 50 μm, with different pore sizes, meeting the needs of high performance chromatographic (HPLC) analysis in the lab and also preparative separation in industrial scale.


Particle Size

Pore Size

Base Material

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Looking for ideal Silica Gel Buy Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the HPLC Analysis Buy are quality guaranteed. We are China Origin Factory of Separation of Organic Compounds. If you have any question, please feel free to contact us.

Product Categories : Chromatography Media - Monodisperse > Silica –based Chromatography Media

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